Viral mutations – Communicable Diseases Research

Decavanadate interactions with the elements of the SARS-CoV-2 spike protein highlight the potential role of electrostatics in disrupting the infectivity cycle

SARS-CoV-2 스파이크 단백질 요소와의 Decavanadate 상호 작용은 감염 주기를 방해하는 정전기의 잠재적 역할을 강조합니다

Article

Published on 2022-09-012022-09-11
Journal: Journal of inorganic biochemistry
[Category] COVID19(2023년), SARS, 치료제,

Dual Inhibition of HIV-1 and Cathepsin L Proteases by Sarcandra glabra

Article

Published on 2022-08-292022-11-15
Journal: Molecules
[Category] SARS, 치료제,

COVID-19 Variant Detection with a High-Fidelity CRISPR-Cas12 Enzyme

고충실도 CRISPR-Cas12 효소를 사용한 COVID-19 변이체 탐지

Article

Published on 2022-07-202022-09-11
Journal: Journal of Clinical Microbiology
[Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제,

[키워드] Analysis Assay validation circulating variant clinical sample clinical samples Concordance COVID-19 COVID-19 patient COVID-19 patients CRISPR CRISPR-Cas12 detection DETECTR Diagnostic method enzyme Enzymes faster followed by Genome sequencing guide RNAs identify infection control isothermal amplification L452R Laboratory test Laboratory tests LAMP Loop-mediated isothermal amplification Mutation mutations N501Y nucleotide omicron Patient polymorphism public health real-time RT-PCR RNAs SARS Coronavirus SARS coronavirus 2 SARS-CoV-2 SARS-CoV-2 lineage SARS-CoV-2 variant SARS-CoV-2 variants Sequencing single nucleotide Single nucleotide polymorphism SNP Surveillance target the SARS-CoV-2 Treatment treatment of COVID-19 patients utility variant variants Viral mutations viral mutations. whole-genome sequencing
[DOI] 10.1128/jcm.00261-22 PMC 바로가기 [Article Type] Article

Mutations in SARS-CoV-2 are on the increase against the acquired immunity

획득 면역에 대한 SARS-CoV-2의 돌연변이 증가 추세

Article

Published on 2022-07-112022-09-11
Journal: PLoS ONE
[Category] COVID19(2023년), SARS, 변종,

[키워드] accumulated mutation accumulated mutations acquired immunity administration animals approach booster vaccination booster vaccinations caused characterisation COVID-19 pandemic COVID-19 vaccine COVID-19 vaccines effective Effectiveness Efficacy Evolution example Healthcare system humans Immunity infecting Infection lockdowns monovalent Mortality mRNA mutated Mutation New occur omicron Omicron variant other variants pandemic pathogenic patients PCA pressure provided question rate of infection resulting SARS-CoV-2 Spread strain Strains sustainability Taiwan Vaccine variant variants viral mutation Viral mutations
[DOI] 10.1371/journal.pone.0271305 PMC 바로가기 [Article Type] Article

Duration of infectious viral shedding in patients with mild to moderate COVID-19 treated with REGN-CoV2

REGN-CoV2로 치료받은 경증 내지 중등도의 COVID-19 환자에서 감염성 바이러스 배출 기간

Article

Published on 2022-07-012022-09-11
Journal: Journal of infection and chemotherapy : official j
[Category] COVID19(2023년), SARS, 변종, 진단, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antiviral effect approved caused Clinical course Clinical efficacy collected coronavirus coronavirus disease COVID-19 Culture Delta delta variant drug Duration effective Efficacy groups Hiroshima Infection inhibitory concentration investigated Isolation Mild Mild disease mild to moderate mild to moderate disease Moderate COVID-19 moderate disease New Patient patients with COVID-19 PCR testing performed Pharyngeal swab reduced REGN-CoV2 respiratory SARS-CoV-2 severe acute respiratory syndrome Coronavirus significantly shorter Spread strain study period treated Treatment treatment methods university Viral viral culture viral mutation Viral mutations viral shedding Viral shedding. virus virus culture virus strain with mild disease
[DOI] 10.1016/j.jiac.2022.03.013 PMC 바로가기 [Article Type] Article

High throughput SARS-CoV-2 variant analysis using molecular barcodes coupled with next generation sequencing

차세대 시퀀싱과 결합된 분자 바코드를 사용하여 처리량이 높은 SARS-CoV-2 변이체 분석

Article

Published on 2022-06-212022-09-11
Journal: PLoS ONE
[Category] COVID19(2023년), MERS, SARS, 변종, 진단,

CoV2K model, a comprehensive representation of SARS-CoV-2 knowledge and data interplay

CoV2K 모델, SARS-CoV-2 지식 및 데이터 상호 작용의 포괄적 표현

Article

Published on 2022-06-012022-09-11
Journal: Scientific Data
[Category] COVID19(2023년), SARS, 변종,

[키워드] Abstract aggregate API co-occurrence COVID-19 pandemic domain Effects Evolution exploration Genome graph information interactions knowledge organization outbreak provide Research resource resources SARS-CoV-2 SARS-CoV-2 virus the SARS-CoV-2 variants Viral mutations while
[DOI] 10.1038/s41597-022-01348-9 PMC 바로가기 [Article Type] Article

Impact of SARS-CoV-2 Variants on the Analytical Sensitivity of rRT-PCR Assays

rRT-PCR 분석의 분석 감도에 대한 SARS-CoV-2 변이체의 영향

Article

Published on 2022-04-202022-09-11
Journal: Journal of Clinical Microbiology
[Category] COVID19(2023년), SARS, 변종, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affected Alpha analytical sensitivity assays Beta Chinese coronavirus country Critical Delta delta variant diagnostic E gene Efficacy Efficiency evaluate Evolution Gamma had no highlight Immune escape Impact Liferiver management MS2 Mutation N gene no significant effect omicron optimization ORF1ab gene pandemic pathogenicity PCR amplification Prevention and control regions reverse transcriptase reverse transcriptase PCR rRT-PCR rRT-PCR. SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 variant SARS-CoV-2 variants sensitivity severe acute respiratory syndrome Coronavirus significant effect strategic management Transmissibility variant viral mutation Viral mutations virus Virus-like particle virus-like particles were used
[DOI] 10.1128/jcm.02374-21 PMC 바로가기 [Article Type] Article

Predicted impact of the viral mutational landscape on the cytotoxic response against SARS-CoV-2

SARS-COV-2에 대한 세포 독성 반응에 대한 바이러스 돌연변이 풍경의 영향 예측 된 영향

Research Article

Published on 2022-02-102022-09-10
Journal: PLoS Computational Biology
[Category] COVID19(2023년), Fulltext, MERS, SARS, 변종,

[키워드] accumulation adaptive affected affecting Algorithm allele Allele families allele family alleles antibodies Asian Author C-terminal change changes in Cluster complexity country COVID-19 susceptibility Critical Cytotoxic T cell deletions eight epitope Epitopes escape escape mutation event except for extreme facilitated genetic background genetic variability genetics Genome genomic HLA class I human allele human population humans immune evasion immune response independent information integration involved isolate isolates Ligand ligands local outbreaks Mutation mutations NCBI Neutralizing occurred pandemic Pandemics Population predicted Prevent Primary infection Protective proteome protocol reduction Region SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 proteome selective subpopulations Substitution Support surpassed Surveillance susceptible T cell T cell response the SARS-CoV-2 unlikely Variability variant variants Viral viral genome viral genomes viral mutation Viral mutations viral variant virus
[DOI] 10.1371/journal.pcbi.1009726 PMC 바로가기 [Article Type] Research Article

Mitigating Covid-19 in the face of emerging virus variants, breakthrough infections and vaccine hesitancy

새로운 바이러스 변종, 획기적인 감염 및 백신 주저에 직면하여 Covid-19 완화

Review

Published on 2022-02-012022-09-11
Journal: Journal of autoimmunity
[Category] COVID19(2023년), MERS, SARS, 변종, 진단,

[키워드] Antibody Response approach B cell B cell memory being booster Breakthrough infection breakthrough infections Cell condition conserved COVID-19 virus creating Critical death Delta disease effective evade facilitate follicular Germinal center Global vaccination helper cells Hospitalization Immunity immunization Interaction multivalent vaccine mutate Mutation notable omicron Omicron variant Omicron variants pandemic Perspective Proteins public health emergency resulting RNA RNA virus robust SARS-CoV-2 Second-generation vaccines Spread T follicular helper cells the antibody response translational Transmissibility Transparency vaccination Vaccine Vaccine hesitancy Vaccines variant variants variants of SARS-CoV-2 variants. Viral viral mutation Viral mutations Viral protein Viral proteins virus virus variants
[DOI] 10.1016/j.jaut.2021.102792 PMC 바로가기 [Article Type] Review